Investigating Distinct and Overlapping Mechanisms in TDP-43 Proteinopathies, including in LATE, FTD and other ADRDs (R01 - Clinical Trial Not Allowed)
Key Information
Due Date: October 4, 2024
Agency: U.S. Department of Health and Human Services (HHS)
Source: Federal
Funding Category:
Health & Human Services
Funding Amount: $500,000
Funding Type: Grant, Government
Match Required: No
Contact Info:
grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Overview
To be specific, the focus lies on unveiling a deeper understanding of the mechanisms behind TDP-43 pathology and the outcomes this proteinopathy presents in patients, aiming to figure out causal relationships. Another critical area the grant supports is the exploration of how TDP-43 interacts with other co-pathologies, such as TMEM106B.
Furthermore, the grant encourages comparative studies between different TDP-43 proteinopathies, such as LATE, with or without AD-NC, and diseases like FTD and/or ALS. The comparisons could span various research areas such as mechanisms, molecular and cellular structures, genetic variations, '-omic' research methods, anatomical correlations, neuropathological differences, and other relevant aspects.
Key Dates
Open Date: February 6, 2024
Application Due Date: October 4, 2024
Estimated Award Date: Not Specified
Additional Details
Eligible Activities
- Research and Development
Eligible Applicants
- State governments
- County governments
- City, village or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments(Federally recognized)
- Public housing authorities/ Indian housing authorities
- Native American tribal organizations(other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS
- other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others