Understanding Mechanisms and Outcomes of Trained Immunity (R01 Clinical Trial Not Allowed)

This Grant Notice is for the Understanding Mechanisms and Outcomes of Trained Immunity program, which does not allow for a clinical trial. The aim of this funding opportunity is to advance research concerning the fundamental processes and indicators of trained immunity, otherwise known as innate immune memory. The research to be supported by this grant should delve into the practical implications of trained immunity. It should revolve around: the development and functionalities of the immune system, immunity derived from vaccination or naturally occurring infections, and its links with allergic diseases, autoimmunity or the rejection of transplanted organs, tissues, or cells.