Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
Key Information
Due Date: October 14, 2026
Agency: U.S. Department of Health and Human Services (HHS)
Source: Federal
Funding Category:
Health & Human Services
Funding Amount: Not Specified
Funding Type: Cooperative Agreement, Government
Match Required: No
Contact Info:
grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Overview
The grant is open to applicants that have already validated the performance of their assays in specimens that are similar to those in the intended clinical use. This implies a focus on existing, tested technology rather than early-stage development. The initiative encourages simultaneous development and validation of assays to measure multiple markers, including those related to immune responses. This is noteworthy as immunotherapies increasingly work in tandem with chemotherapies and radiation therapies to enhance long-term anti-cancer responses.
Funded under the UH3 mechanism, the grant aims to support the clinical validation of established assays for up to three years. This process of validation will utilize specimens from either retrospective or prospective clinical trials or studies. The grant can also be used for the validation of existing assays intended for use in other trials, observational studies, or population studies.
Additionally, projects aimed at unifying clinical laboratory tests will be eligible for funding. These include studies into the performance and reproducibility of assays across various clinical laboratories.
Applying for this grant requires a collaborative approach, bringing together multiple disciplines, including scientific investigators, oncologists, statisticians, and clinical laboratory scientists. The ultimate objective of this grant is to validate assays to the point of being able to incorporate them into clinical trials or studies as investigational assays.
Key Dates
Open Date: October 31, 2023
Application Due Date: October 14, 2026
Estimated Award Date: Not Specified
Additional Details
Eligible Activities
- Research and Development
Eligible Applicants
- State governments
- County governments
- City, village or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Small businesses