Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)
Key Information
Due Date: October 14, 2026
Agency: U.S. Department of Health and Human Services (HHS)
Source: Federal
Funding Category:
Health & Human Services
Funding Amount: Not Specified
Funding Type: Cooperative Agreement, Government
Match Required: No
Contact Info:
grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Overview
Potential applicants should have assays that function effectively on human samples and hold significant potential for development into clinical assessments. As current cancer treatments often combine chemotherapy or radiation with immunotherapies, a focus on assays that can measure multiple markers, including immune markers, would be encouraged.
The grant will be divided into two phases. The UH2 phase requires the analytical validation of assays in the context of molecular, cellular and imaging markers, to be achieved within a period of two years. In the UH3 phase, the grant supports the clinical validation of these analytically validated assays for a period of up to three years. These tests will utilize well-annotated biospecimens from either retrospective or prospective clinical studies.
The grant can also be used to validate existing assays for use in a variety of cancer clinical trials, observational studies or population-oriented studies. Efforts to standardize clinical laboratory tests are also encouraged and could include investigations into the performance consistency and reproducibility of assays across several clinical laboratories.
This funding opportunity emphasizes a need for multi-disciplinary collaboration; thus, proposed projects should involve partnerships among scientific researchers, oncologists, statisticians, and clinical laboratory scientists.
Key Dates
Open Date: November 1, 2023
Application Due Date: October 14, 2026
Estimated Award Date: Not Specified
Additional Details
Eligible Activities
- Research and Development
Eligible Applicants
- State governments
- County governments
- City, village or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Small businesses