Targeting Inflammasomes in HIV and Substance Use (R21 Clinical Trial Not Allowed)

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Key Information

Due Date: March 13, 2025


Agency: U.S. Department of Health and Human Services (HHS)


Source: Federal


Funding Category:

Health & Human Services

Funding Amount: Not Specified


Funding Type: Grant


Match Required: No


Contact Info: grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

Overview

This grant proposal, titled "Targeting Inflammasomes in HIV and Substance Use", will not permit clinical trials. It aims to stimulate scientific research into better understanding the role inflammasomes play in the neuropathological changes caused by either short-term or long-term exposure to drugs and HIV infection. By exploring the function of inflammasomes in relation to drug and virus-induced immune response, research could potentially identify molecular markers and brain immune cells that are associated with HIV-1 infection or progression of diseases in substance users. Additionally, new therapies could be developed to regulate inflammasome activity, offering potential treatments for the neuroinflammation and immune disruption caused by these processes.
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Key Dates

Open Date: October 17, 2023


Application Due Date: March 13, 2025


Estimated Award Date: Not Specified

Additional Details

Eligible Activities

  • Research and Development

Eligible Applicants

  • State governments
  • County governments
  • City, village or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Private institutions of higher education
  • Small businesses

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