Exploratory studies to investigate mechanisms of HIV infection, replication, latency, and/or pathogenesis in the context of substance use disorders (R01 Clinical Trial Not Allowed)

This is a grant for exploratory research studies focused on unfolding the mechanisms of HIV - how it infects, replicates, lies dormant (latency), and/or pathogenesis (the development of the disease), specifically within the context of substance use disorders. The phrase "(R01 Clinical Trial Not Allowed)" indicates that researchers are not permitted to conduct clinical trials under this grant. They may, however, investigate these mechanistic aspects of HIV in relation to substance use disorders (SUDs) including HIV-associated Neurocognitive Disorders (HAND). The purpose of awarding this grant is to support and promote studies that can answer key questions in this specific field.