Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)

This text announces a grant offered by the Chemical Countermeasures Research Program (CCRP) Initiative. The grant is called "Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids." This grant is not intended to support clinical trials under the R01 scheme. Instead, this funding is meant to support groundbreaking research designed to discover and validate mechanisms, signaling pathways, and therapeutic targets that can be used to understand and reverse the harmful effects of an overdose caused by acute exposure to ultra-potent synthetic opioids.

In addition to this, the grant also seeks to fund mechanistic studies about the long-term or delayed harmful physiological effects that occur after a person has been acutely exposed to ultra-potent synthetic opioids. The aim of this research is to delve deeper into the severe impacts of UPS opioid overdoses and the potential measures to combat this issue.