NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant (UG1 Clinical Trial Required)

The National Eye Institute (NEI) offers a grant called 'NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant'. It requires the undertaking of a clinical trial (classified as UG1). The purpose of these grants is to support large-scale clinical trials led by investigative teams, particularly those conducting human gene-transfer studies, stem cell therapy trials, or other complex, high-stake clinical trials that incur extensive resource usage or pose significant safety concerns.

These projects are multifaceted, with a high degree of public health significance, necessitating a clear outline of the study's organization, including a thorough understanding of roles and responsibilities. They need close monitoring and oversight to ensure effective performance.

The funding opportunity outlined in this notice targets studies that intend to evaluate interventions meant to screen, diagnose, prevent, or treat vision disorders. Alternatively, the studies could also compare the effectiveness of two or more pre-established interventions.

Typically, the UG1-supported studies by NEI are funded as a group of individual component grants. These include the Chairs Grant, the Coordinating Center, and Resource Centers when suitable. This specific Notice of Funding Opportunity (NOFO) is encouraging applications specifically for the Coordinating Center grant. The Coordinating Center grant outlines the responsibilities and operations of the Coordinating Center.