Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is providing a funding opportunity under the Small R01s for Clinical Trials scheme. The aim of this grant is to support small-scale, initial clinical trials that focus on the prevention and treatment of diseases that fall within the NIDDK's scope.

These early-stage trials should be geared towards providing foundational data to help shape larger, future trials. The projects should focus on gathering preliminary data on the effects of the intended intervention, testing the feasibility of participant recruitment and retention, and gauging overall study conduct.

Applicants seeking funding under this scheme need to present well-defined aims and objectives, and illustrate the high potential for their trials to pave the way for more extensive, hypothesis-based studies. Such studies should further our understanding, diagnosis, prevention, or treatment of the targeted diseases. They should also have the potential to significantly impact clinical practice and public health policy.

Importantly, it's not required for the preliminary data to already establish the intervention's efficacy. The main goal is to kickstart the investigation process with good-faith, scientific explorations providing a solid base for future larger scale, in-depth trials.