Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trial Required)

This grant, titled "Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery," requires the conducting of a clinical trial and is focused on exploring the impact of social relationships on health outcomes, including illness, recovery, and overall wellbeing. Applications are invited from research projects that delve into understanding the patterns, underlying factors, and pathways of these connections.

Projects eligible for this grant are those categorized as mechanistic studies, defined as studies which aim to comprehend the workings of a treatment, biological or behavioral process, or disease. For instance, the clinical trial could be exploring how social isolation affects a certain health condition (refer NOT-AT-20-001 and NOT-MH-19-006 for details).

Please note that clinical trials aimed at influencing clinical outcomes, testing intervention safety, proving clinical efficacy, or measuring intervention effect size on outcomes are not applicable for this grant. The studies should focus on understanding the fundamental aspects of the phenomenon without immediate application to specific processes or products.

For researchers interested in conducting basic science experimental studies involving humans, please consider the companion grant, TEMP-14931 "Research on Health, Wellbeing, Illness, and Recovery." For studies including animal research models or human observational studies, consider the companion grant, TEMP-14934 "Research on Biopsychosocial Factors" where clinical trials are not mandatory.