Mechanisms of Alcohol Tolerance (R21/R33 Clinical Trial Optional)

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Key Information

Due Date: September 7, 2024


Agency: U.S. Department of Health and Human Services (HHS)


Source: Federal


Funding Category:

Health & Human Services

Funding Amount: $581,371


Funding Type: Grant


Match Required: No


Contact Info: grantsinfo@nih.gov
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Overview

The grant, named "Mechanisms of Alcohol Tolerance (R21/R33 Clinical Trial Optional)", seeks to explore the factors that contribute to the development of alcohol use disorder. It aims to specifically investigate the biological sensors, managing elements at the cellular, molecular or network level that regulate tolerance and sensitivity to alcohol.

The goals of the grant also include establishing theoretical models that can accurately predict the development of alcohol tolerance and progression into an alcohol use disorder. This grant will be implemented in two stages, the R21 phase and the R33 phase.

The initial phase, R21, may involve secondary data analysis or pilot studies to develop the hypotheses. This is followed by the R33 phase which expands on research to test those hypotheses. The shift from the R21 phase to the significantly detailed R33 phase will be decided by the NIAAA program staff. The decision will be based upon successfully meeting the specific milestones set for the first stage. Please note that the inclusion of a clinical trial is optional in this grant.

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Key Dates

Open Date: June 22, 2021


Application Due Date: September 7, 2024


Estimated Award Date: Not Specified

Additional Details

Eligible Activities

  • Research and Development

Eligible Applicants

  • State governments
  • County governments
  • City, village or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Private institutions of higher education
  • Small businesses

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