Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)

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Key Information

Due Date: April 3, 2026


Agency: U.S. Department of Health and Human Services (HHS)


Source: Federal


Funding Category:

Health & Human Services

Funding Amount: $581,371


Funding Type: Grant


Match Required: No


Contact Info: grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

Overview

The NICHD manages a top-tier Chemical Synthesis and Optimization Facility that is part of a program named Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed). This facility is geared towards the development of non-hormonal contraceptives and other products related to reproductive health.

It has been well-equipped to conduct preclinical services. Some of these include studies that enable Investigational Device Exemption (IDE) or Investigational New Drug (IND). These studies involve a wide range of processes such as protein generation, X-ray crystallography, high throughput screening, establishing structure-activity relationships, generating a hit-to-lead, and studying drug metabolism.

The overall aim of this facility is to ensure it can produce a preclinical candidate that is eligible for IND/IDE studies. The candidate must provide a safe therapeutic alternative in the realm of contraception and other areas connected to reproductive health. Provision of this service hinges on contractor availability and whether there is sufficient funding.

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Key Dates

Open Date: May 19, 2023


Application Due Date: April 3, 2026


Estimated Award Date: Not Specified

Additional Details

Eligible Activities

  • Research and Development

Eligible Applicants

  • State governments
  • County governments
  • City, village or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Private institutions of higher education
  • Small businesses

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