Discovery Gateway to Reproductive Health Innovation

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks to establish a single Discovery Gateway to Reproductive Health Innovation, a comprehensive knowledgebase designed to advance research on male and female indications such as preeclampsia, endometriosis, preterm birth, infertility, and uterine fibroids. This initiative will expand shared resources and essential infrastructure for the biomedical research community.

The Gateway will facilitate integration of existing clinical, pharmacogenomic, and multi-omic data in order to address critical knowledge gaps. By providing open-access, this web-based visualization platform will empower scientists to generate new insights that extend far beyond the scope of individual research efforts. Ultimately, the overarching goal is to catalyze the discovery of new treatments and cures. By identifying potential disease mechanisms, effector genes, biomarkers, and drug targets, the Gateway will drive the development of innovative commercial products and accelerate public-private partnerships.

The Discovery Gateway supports multiple implementation recommendations made by the Task Force on Research Specific to Pregnant Women and Lactating Women (PRGLAC; https://www.nichd.nih.gov/about/advisory/PRGLAC). Grant authorities that allow NICHD to forecast this opportunity are as follows: 42 U.S.C. 281 (Sec. 401); 42 U.S.C. 285g (Sec. 448); 42 USC 284h (Sec. 409D).