HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
Key Information
Due Date: October 30, 2026
Agency: United States Department of Health and Human Services
Source: Federal
Website: View Website
Funding Categories:
Funding Amount: Not Specified
Funding Type: Grant
Match Required: No
Status: Posted
Contact Info:
NCCIHDERFunding@nih.gov
NCCIH Program Officer NCCIHDERFunding@nih.gov
NCCIH Program Officer NCCIHDERFunding@nih.gov
Overview
The NIH Helping to End Addiction Long-term® (HEAL) Initiative is releasing this Notice of Funding Opportunity (NOFO) to support a phased mechanistic clinical research program focusing on understudied biological mechanisms that drive joint pain. The phased projects supported by this program (of up to five years total in duration) will first identify and validate multi-tissue mechanisms underlying joint pain, then test non-pharmacologic or multimodal interventions that directly target these mechanisms. The initiative responds to priorities identified in the 2023 HEAL Whole Joint Pain Workshop and supports the broader goals of the NIH HEAL Initiative and the Make America Healthy Again vision by advancing safe, non-addictive, and prevention-oriented approaches to chronic pain.
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Additional Info
Posted Date: September 28, 2026
Application Due Date: October 30, 2026
Estimated Award Date: Not Specified
Eligible Applicants:
- Native American tribal governments (Federally recognized)
- Others
- City or township governments
- Small businesses
- County governments
- Special district governments
- Public and State controlled institutions of higher education
- For profit organizations other than small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Private institutions of higher education
- Independent school districts
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
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