Strategies to Innovate Emergency Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

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Key Information

Due Date: March 4, 2027


Agency: United States Department of Health and Human Services


Source: Federal


Website: View Website


Funding Categories:

Funding Amount: Not Specified


Funding Type: Cooperative Agreement


Match Required: No


Status: Forecasted


Contact Info: NINDS_SIREN@ninds.nih.gov
NINDS Department of Emergency Medicine Please contact via e-mail.

Overview

The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care.

Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.

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Additional Info

Posted Date: August 13, 2026


Application Due Date: March 4, 2027


Estimated Award Date: Not Specified


Eligible Applicants:

  • Private institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Public housing authorities/Indian housing authorities
  • County governments
  • State governments
  • Public and State controlled institutions of higher education
  • Special district governments
  • City or township governments
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • For profit organizations other than small businesses
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Small businesses
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