Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)

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Key Information

Due Date: June 16, 2028


Agency: United States Department of Health and Human Services


Source: Federal


Website: View Website


Funding Categories:

Funding Amount: Not Specified


Funding Type: Grant


Match Required: No


Status: Posted


Contact Info: NIDA_DNB_BCNB_r61@nih.gov
Division of Neuroscience and Behavior (DNB) NIDA_DNB_BCNB_r61@nih.gov

Overview

This notice of funding opportunity (NOFO) uses a R61/R33 Phased Innovation Award activity code to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying substance use disorders (SUD), including fundamental circuitry and behavior relevant to substance use. For projects not requiring a phased research approach, applicants are encouraged to apply under a different funding activity code (e.g., PA-25-305 "Research Project Grant (Parent R01 Clinical Trial Required)" or its subsequent reissue).
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Additional Info

Posted Date: August 31, 2026


Application Due Date: June 16, 2028


Estimated Award Date: Not Specified


Eligible Applicants:

  • For profit organizations other than small businesses
  • Small businesses
  • Private institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Special district governments
  • City or township governments
  • Others
  • Public and State controlled institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • State governments
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • County governments
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