INCLUDE Project: Exploratory/developmental Research Awards for down Syndrome (R21 Clinical Trial Not Allowed)

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Key Information

Due Date: June 15, 2028


Agency: United States Department of Health and Human Services


Source: Federal


Website: View Website


Funding Categories:

Funding Amount: $1,000,000


Funding Type: Grant


Match Required: No


Status: Posted


Contact Info: DownSyndromeINCLUDE@mail.nih.gov
The INCLUDE Project DownSyndromeINCLUDE@mail.nih.gov

Overview

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
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Additional Info

Posted Date: May 12, 2026


Application Due Date: June 15, 2028


Estimated Award Date: Not Specified


Eligible Applicants:

  • Special district governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • State governments
  • For profit organizations other than small businesses
  • City or township governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others
  • Independent school districts
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • County governments
  • Public housing authorities/Indian housing authorities
  • Private institutions of higher education
  • Small businesses
  • Native American tribal governments (Federally recognized)
  • Public and State controlled institutions of higher education
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