INCLUDE Project: Transformative Research Awards for down Syndrome (R01 Clinical Trial Not Allowed)

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Key Information

Due Date: June 15, 2028


Agency: United States Department of Health and Human Services


Source: Federal


Website: View Website


Funding Categories:

Funding Amount: $3,000,000


Funding Type: Grant


Match Required: No


Status: Posted


Contact Info: DownSyndromeINCLUDE@mail.nih.gov
The INCLUDE Project DownSyndromeINCLUDE@mail.nih.gov

Overview

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.
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Additional Info

Posted Date: May 12, 2026


Application Due Date: June 15, 2028


Estimated Award Date: Not Specified


Eligible Applicants:

  • County governments
  • Native American tribal governments (Federally recognized)
  • City or township governments
  • Public housing authorities/Indian housing authorities
  • Public and State controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Independent school districts
  • Others
  • For profit organizations other than small businesses
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Small businesses
  • State governments
  • Special district governments
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