Single Source: Childhood Cancer Survivor Study (U24 Clinical Trial Not Allowed)

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support the continuation of the Childhood Cancer Survivor Study (CCSS) that investigates the long-term morbidity and mortality associated with cancer treatments. The CCSS represents a multi-institutional, multidisciplinary collaborative research resource that currently has health-related data from 38,000 or more 5-year survivors of pediatric and adolescent cancer patients with a comparison sibling control cohort. This NOFO seeks to obtain additional age-related longitudinal information from the current cohort of survivors and to include pediatric cancer survivors receiving modern therapies. The goal of the CCSS is to serve as a data resource and a biorepository for researchers. The objectives are to use the resources to conduct cancer risk assessments, observational and intervention-based research studies associated with long-term outcomes across the life span of survivors with the intent of improving cancer treatments. This is a Forecast for a single source that will invite application(s) from eligible organization(s) to apply. Please see the Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.