Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (Rapids) (R01 Clinical Trial Required)

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Key Information

Due Date: October 11, 2026


Agency: United States Department of Health and Human Services


Source: Federal


Website: View Website


Funding Categories:

Funding Amount: $5,500,000


Funding Type: Grant


Match Required: No


Status: Posted


Contact Info: DTRcommunications@nih.gov
Division of Translational Research DTRcommunications@nih.gov

Overview

The purpose of this notice of funding opportunity (NOFO) is to elucidate the key components of the therapeutic effects of rapid-acting psychotropic interventional drugs (RAPIDs) by addressing the methodological challenges involved with these clinical trials. In addition, this NOFO seeks to advance understanding of how RAPIDs and adjunctive psychosocial interventions can be optimally delivered, monitored, and sustained over time to enhance effectiveness and generalizability. The NOFO will support studies designed to enhance the rigor of RAPID clinical trial design, which will ultimately increase the interpretability of the data and the generalizability of the results.
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Additional Info

Posted Date: April 29, 2026


Application Due Date: October 11, 2026


Estimated Award Date: Not Specified


Eligible Applicants:

  • State governments
  • City or township governments
  • Small businesses
  • Native American tribal governments (Federally recognized)
  • Others
  • Private institutions of higher education
  • Public housing authorities/Indian housing authorities
  • For profit organizations other than small businesses
  • Public and State controlled institutions of higher education
  • Independent school districts
  • Special district governments
  • County governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
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