NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional)
Key Information
Due Date: September 3, 2026
Agency: United States Department of Health and Human Services
Source: Federal
Funding Categories:
Funding Amount: $8,000,000
Funding Type: Grant
Match Required: No
Status: Forecasted
Contact Info:
Transformative_Awards@mail.nih.gov
Transformative_Awards@mail.nih.gov
Transformative_Awards@mail.nih.gov
Overview
The NIH Director’s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director’s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.
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Key Dates
Posted Date: January 6, 2026
Application Due Date: September 3, 2026
Estimated Award Date: Not Specified
Additional Details
Eligible Applicants
- City or township governments
- For profit organizations other than small businesses
- Native American tribal governments (Federally recognized)
- Small businesses
- Private institutions of higher education
- Others
- State governments
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Special district governments
- Public and State controlled institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Independent school districts