NHLBI TOPMed: Omics Phenotypes of Heart, Lung, and Blood Disorders (X01 - Clinical Trial Not Allowed)

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Key Information

Due Date: May 8, 2028


Agency: United States Department of Health and Human Services


Source: Federal


Website: View Website


Funding Categories:

Funding Amount: Not Specified


Funding Type: Grant


Match Required: No


Status: Posted


Contact Info: grantsinfo@nih.gov
NIH Grants Information grantsinfo@nih.gov

Overview

This Notice of Funding Opportunity (NOFO) invites applications to use NHLBI-funded TransOmics for Precision Medicine (TOPMed) program to generate a large volume of integrated genetic and multi-omics data to facilitate discovery of the molecular mechanisms of Heart, Lung, Blood, and Sleep (HLBS) disorders. No funding will be provided under this NOFO. The genomic data and related phenotypic data will be deposited in a public NIH-designated controlled-access database such as the database for Genotypes and Phenotypes (dbGaP) and NHLBIs BioData Catalyst (BDC). The overall goal is to move from simply cataloguing genetic associations to understanding how genetic factors contribute to HLBS diseases at the molecular and cellular levels. This transformation will help move TOPMed from genetic Map to Mechanism with potential applications of AI and ML tool sets where possible, enabling functional genomics research that will accelerate mechanistic personalized medicine
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Additional Info

Posted Date: September 22, 2025


Application Due Date: May 8, 2028


Estimated Award Date: Not Specified


Eligible Applicants:

  • For profit organizations other than small businesses
  • Native American tribal governments (Federally recognized)
  • Private institutions of higher education
  • Others
  • State governments
  • Public housing authorities/Indian housing authorities
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public and State controlled institutions of higher education
  • Special district governments
  • Independent school districts
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • City or township governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • County governments
  • Small businesses
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