Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
Key Information
Due Date: February 17, 2028
Agency: United States Department of Health and Human Services
Source: Federal
Funding Categories:
Funding Amount: Not Specified
Funding Type: Grant
Match Required: No
Status: Posted
Contact Info:
grantsinfo@nih.gov
NIH Grants Information grantsinfo@nih.gov
NIH Grants Information grantsinfo@nih.gov
Overview
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method or agent that is selective for one or more targets within that target class. This NOFO is intended to jumpstart research that demonstrates innovative strategies to modulate targets that cannot be addressed by established therapeutic types, furthering the development of methods and/or agents selective for undruggable target classes.
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Key Dates
Posted Date: June 17, 2025
Application Due Date: February 17, 2028
Estimated Award Date: Not Specified
Additional Details
Eligible Applicants
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Small businesses
- Public housing authorities/Indian housing authorities
- Public and State controlled institutions of higher education
- For profit organizations other than small businesses
- Others
- Special district governments
- Independent school districts
- Native American tribal governments (Federally recognized)
- State governments
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education